Review



70k tkov3 library  (Addgene inc)


Bioz Verified Symbol Addgene inc is a verified supplier  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 94

    Structured Review

    Addgene inc 70k tkov3 library
    70k Tkov3 Library, supplied by Addgene inc, used in various techniques. Bioz Stars score: 94/100, based on 92 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/70k+tkov3+library/Toronto+KnockOut+(TKO)+CRISPR+Library+-+Version+3+(Pooled+Libraries+%2390294%2C+%23125517)/bio_rxiv__64898__2026__03__16__712096-331-26-29
    Average 94 stars, based on 92 article reviews
    70k tkov3 library - by Bioz Stars, 2026-09
    94/100 stars

    Images

    Related Articles

    CRISPR:

    Article Title: Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma.
    Article Snippet: .. We performed CRISPR-Cas9 based genome-wide knockout screening on three PFA cell cultures (MDT-PFA2, MDT- PFA4, and MDT-PFA5) using the 70K TKOv3 library (Addgene #90294) as described in previous study (Hart et al., 2015; Hart and Moffat, 2016; MacLeod et al., 2019). ..

    Article Title: Phosphorylation-driven Targeted Protein Degradation of Oncogenic β-catenin
    Article Snippet: .. The CRISPR/Cas9 KO screen was performed in DLD-1 CTNNB1 eGFP-FRB*/eGFP-FRB* cells (clone #43) after stable, lentiviral integration of CSNK1D-FKBP12 F36V -HAtag_T2A_Hygromycin and hygromycin selection using the 70K TKOv3 library (Addgene Pooled Library #90294)( ). ..

    Article Title: Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma
    Article Snippet: .. We performed CRISPR-Cas9 based genome-wide knockout screening on three PFA cell cultures (MDT-PFA2, MDT- PFA4, and MDT-PFA5) using the 70K TKOv3 library (Addgene #90294) as described in previous study ( Hart and Moffat, 2016a ; MacLeod et al., 2019 ). ..

    Article Title: Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells.
    Article Snippet: Survival data was plotted and analyzed using GraphPad Prism. .. CRISPR-Cas9 screens were performed using the 90K TKOv1 library (G523NS, G361NS, G440NS, G432NS, G510NS, G472NS, G564NS, G477NS) (Hart et al., 2015) (Addgene #1000000069) or 70K TKOv3 library (G583NS, G549NS, HF6562, HF7450) (Hart et al., 2017) (Addgene #90294). ..

    Article Title: Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma
    Article Snippet: .. Methods for collection, library preparation, alignment and QC are according to the previously published article. . Genome-wide knockout screen: We performed CRISPR-Cas9 based genome-wide knockout screening on three PFA cell cultures (MDT-PFA2, MDT- PFA4, and MDT-PFA5) using the 70K TKOv3 library (Addgene #90294) as described in previous study ( Hart and Moffat, 2016a ; MacLeod et al., 2019 ). ..

    Article Title: Identification of Injury-Response State Determinants in Glioblastoma Stem Cells
    Article Snippet: Cells were periodically subjected to testing with the MycoAltert Plus mycoplasma detection kit (Lonza Biosciences) to confirm the absence of contamination. .. CRISPR-Cas9 KO screen was performed as previously described using the 70K TKOv3 library (Addgene Pooled Library #90294)( ; ). ..

    Article Title: Epigenetic maintenance of the injury response state in glioblastoma stem cells
    Article Snippet: .. CRISPR-Cas9 knockout (KO) screen was performed using the 70K TKOv3 library (Addgene Pooled Library #90294) ; 4 × 10 8 cells were transduced with a multiplicity of infection of 0.3 in the presence of 0.8 μg/mL of polybrene and plated into 10 cm plates. ..

    Genome Wide:

    Article Title: Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma.
    Article Snippet: .. We performed CRISPR-Cas9 based genome-wide knockout screening on three PFA cell cultures (MDT-PFA2, MDT- PFA4, and MDT-PFA5) using the 70K TKOv3 library (Addgene #90294) as described in previous study (Hart et al., 2015; Hart and Moffat, 2016; MacLeod et al., 2019). ..

    Article Title: Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma
    Article Snippet: .. We performed CRISPR-Cas9 based genome-wide knockout screening on three PFA cell cultures (MDT-PFA2, MDT- PFA4, and MDT-PFA5) using the 70K TKOv3 library (Addgene #90294) as described in previous study ( Hart and Moffat, 2016a ; MacLeod et al., 2019 ). ..

    Article Title: Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma
    Article Snippet: .. Methods for collection, library preparation, alignment and QC are according to the previously published article. . Genome-wide knockout screen: We performed CRISPR-Cas9 based genome-wide knockout screening on three PFA cell cultures (MDT-PFA2, MDT- PFA4, and MDT-PFA5) using the 70K TKOv3 library (Addgene #90294) as described in previous study ( Hart and Moffat, 2016a ; MacLeod et al., 2019 ). ..

    Knock-Out:

    Article Title: Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma.
    Article Snippet: .. We performed CRISPR-Cas9 based genome-wide knockout screening on three PFA cell cultures (MDT-PFA2, MDT- PFA4, and MDT-PFA5) using the 70K TKOv3 library (Addgene #90294) as described in previous study (Hart et al., 2015; Hart and Moffat, 2016; MacLeod et al., 2019). ..

    Article Title: Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma
    Article Snippet: .. We performed CRISPR-Cas9 based genome-wide knockout screening on three PFA cell cultures (MDT-PFA2, MDT- PFA4, and MDT-PFA5) using the 70K TKOv3 library (Addgene #90294) as described in previous study ( Hart and Moffat, 2016a ; MacLeod et al., 2019 ). ..

    Article Title: Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma
    Article Snippet: .. Methods for collection, library preparation, alignment and QC are according to the previously published article. . Genome-wide knockout screen: We performed CRISPR-Cas9 based genome-wide knockout screening on three PFA cell cultures (MDT-PFA2, MDT- PFA4, and MDT-PFA5) using the 70K TKOv3 library (Addgene #90294) as described in previous study ( Hart and Moffat, 2016a ; MacLeod et al., 2019 ). ..

    Article Title: Epigenetic maintenance of the injury response state in glioblastoma stem cells
    Article Snippet: .. CRISPR-Cas9 knockout (KO) screen was performed using the 70K TKOv3 library (Addgene Pooled Library #90294) ; 4 × 10 8 cells were transduced with a multiplicity of infection of 0.3 in the presence of 0.8 μg/mL of polybrene and plated into 10 cm plates. ..

    Selection:

    Article Title: Phosphorylation-driven Targeted Protein Degradation of Oncogenic β-catenin
    Article Snippet: .. The CRISPR/Cas9 KO screen was performed in DLD-1 CTNNB1 eGFP-FRB*/eGFP-FRB* cells (clone #43) after stable, lentiviral integration of CSNK1D-FKBP12 F36V -HAtag_T2A_Hygromycin and hygromycin selection using the 70K TKOv3 library (Addgene Pooled Library #90294)( ). ..

    Transduction:

    Article Title: Epigenetic maintenance of the injury response state in glioblastoma stem cells
    Article Snippet: .. CRISPR-Cas9 knockout (KO) screen was performed using the 70K TKOv3 library (Addgene Pooled Library #90294) ; 4 × 10 8 cells were transduced with a multiplicity of infection of 0.3 in the presence of 0.8 μg/mL of polybrene and plated into 10 cm plates. ..

    Infection:

    Article Title: Epigenetic maintenance of the injury response state in glioblastoma stem cells
    Article Snippet: .. CRISPR-Cas9 knockout (KO) screen was performed using the 70K TKOv3 library (Addgene Pooled Library #90294) ; 4 × 10 8 cells were transduced with a multiplicity of infection of 0.3 in the presence of 0.8 μg/mL of polybrene and plated into 10 cm plates. ..



    Similar Products

    94
    Addgene inc 70k tkov3 library
    70k Tkov3 Library, supplied by Addgene inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/70k+tkov3+library/Toronto+KnockOut+(TKO)+CRISPR+Library+-+Version+3+(Pooled+Libraries+%2390294%2C+%23125517)/bio_rxiv__64898__2026__03__16__712096-331-26-29
    Average 94 stars, based on 1 article reviews
    70k tkov3 library - by Bioz Stars, 2026-09
    94/100 stars
      Buy from Supplier

    Image Search Results